Our jobs can provide intellectually and socially enriched environments but also be the source of major psychological and physical stressors.As the average full-time worker spends >8 h at work per weekday and remains in the workforce for about 40 years, occupational experiences must be Blenders important factors in cognitive and brain aging.There
Abstract Kainate receptors (KARs) are a subtype of ionotropic glutamate receptor (iGluR) channels, a superfamily of ligand-gated ion channels which mediate the majority of excitatory neurotransmission in the central nervous system.KARs modulate neuronal circuits and plasticity during development and are implicated in neurological disorders, includi
Cerebral Vasospasm is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) which results in delayed cerebral ischemia.Cerebral vasospasm in elective endovascular management of intracranial aneurysms rarely has been reported, and the vasospasm in this situation results from irritation by the endovascular catheter.The choice of intra-ar
Up until recently, it was believed that pharmaceutical drugs and their metabolites enter into the cell to gain access to their targets via simple diffusion across the hydrophobic lipid cellular membrane, at a rate which is based on their lipophilicity.An increasing amount of evidence indicates that the phospholipid bilayer-mediated drug diffusion i